| 释义 |
Cushing's disease
noun[ U ]
medical specialized(alsoCushing disease)uk /ˈkʌʃ.ɪŋz dɪˌziːz/ us /ˈkʊʃ.ɪŋz dɪˌziːz/
a medical condition caused by a tumour(= a mass of diseased cells) in the pituitary gland(= a small organ that produces hormones) in the brain that may cause someone to develop conditions such as obesity, high blood pressure, and diabetes:
Diabetes can occur as a secondary consequence of Cushing's disease.
Radiation of pituitary tumours reduces cortisol levels in about half of adults with Cushing's disease.
Current medical therapies for Cushing's disease primarily focus on adrenal blockade of cortisol production.
Cushing's disease requires surgical removal of the tumour as the first line of treatment.
Cortisol pulsatility is blunted in around 70% of patients with Cushing disease.
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