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unmyelinated adjective anatomy specializeduk /ʌnˈmaɪə.lɪ.neɪ.tɪd/ us /ʌnˈmaɪə.lɪ.neɪ.t̬ɪd/ An unmyelinated nerve is one that does not have a myelin sheath (= a layer that surrounds and protects some nerves): The lower pain threshold in these patients may be caused by abnormal unmyelinated nerve fibres. The peripheral nerves are largely comprised of myelinated and unmyelinated axons, typically grouped in fascicles. A peripheral neuropathy affecting the small myelinated and unmyelinated fibres commonly develops as the disease progresses. The C fibres are unmyelinated and transmit signals more slowly. The primary afferent neurons responsible for histamine-induced itch are unmyelinated C-fibres. SMART Vocabulary: related words and phrases The brain & nervous system abducens nerve abducent nerve accessory nerve alexithymia allism glossopharyngeal nerve grey matter hemispheric hemispherical hindbrain neurofibrillary neurogenic neurogenically neuroglia neuroglial reinnervation reticular formation rhinencephalon rhombencephalon right brain
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